Potensi Antimikroba dan Toksisitas Minyak Atsiri yang Diisolasi dari Biji Jintan (Carum carvi L.)


  • Suryati Suryati Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalas, Indonesia
  • Emil Salim Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalas, Indonesia
  • Gustia Elizar Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalas, Indonesia




Carum carvi L., essential oil, antimicrobial, cytotoxic


Caraway (Carum carvi L.) is one of the oldest medicinal plants found in various countries such as West Asia, North Africa, Pakistan, India, North America, Northern Europe, Iran, Russia, and Indonesia. This plant has been use for traditional medicines to treat digestive disorders, flatulence, colic in infants, headaches, coughs, hypertension, eczema, pneumonia, diabetes, scabies, mouthwash and as an antiseptic. This plant is reported to contain around 1-9% essential oil in the seeds with various components and potential as bioactive compounds. In this study, essential oils were isolated from caraway seeds and determined their chemical content as well as their antimicrobial and toxicity. Isolation of essential oils was carried out by hydrodistillation and analysis of the chemical components of the isolated essential oils was carried out using the Gas Chromatography-Mass Spectrometry (GC-MS) method. The results of the GC-MS analysis showed the presence of 35 compounds with four main compounds, namely carvone (62.54%), limonene (23.39%), and trans-dihydrocarvone (8.20%). The antimicrobial activity test was carried out using the disc diffusion method, which showed strong activity against Staphylococcus aureus at a concentration of  ≥75%, and against the fungus Candida albicans. The results of the toxicity test using the Brine Shrimp Lethality Test (BSLT) method showed that caraway seed essential oil was low toxic against Artemia salina Leach shrimp larvae with an LC50 value 568.3292 mg/L.

Author Biography

Suryati Suryati, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Andalas


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How to Cite

Suryati, S., Emil Salim, & Gustia Elizar. (2022). Potensi Antimikroba dan Toksisitas Minyak Atsiri yang Diisolasi dari Biji Jintan (Carum carvi L.). Jurnal Riset Kimia, 13(2), 198–207. https://doi.org/10.25077/jrk.v13i2.551




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