SENYAWA FENOLIK DARI KULIT BATANG Garcinia cf. cymosa DAN UJI AKTIFITAS ANTIOKSIDAN

Yuliar -, Yunazar Manjang, Syamsul A. Achmad, Sanusi Ibrahim

Abstract

 

ABSTRACT

 

A Phenolic compound was isolated from the bark of Garcinia cf. cymosa. Isolation methods were used are maseration, fractionation, and chromatography. Structure determination was done using spectroscopy methods including IR, H-NMR, C-NMR, DEPT, COSY, HMQC, and HMBC. The result showed that the isolated compound is (-)epicatechin. Antioxidant activity of isolated compound was determined by DPPH method. Isolated compound has antioxidant activity which has IC50 = 41,8 ppm.

 

Keywords : Phenolic, (-)epicatechin, Garcinia cf. cymosa, DPPH

Full Text:

PDF

References

G. S. Joseph, G. K. Jayapraksa, and A. T. Selvi, Antiflatoxigenic and antioxidant activities of Garcinia Extract. Int. Journal of Food Microbology., 101: 153-160, (2005).

Lannang, A. M. Komguem, J., F. N. Ngninzeko, J. Tangmoua, Two xanthone from the steam bark of Garcinia polyantha Oliv. Phytochemistry., 60: 2351-2355, (2005).

Elfita, Santon dan benzofenon dari tubuhan kandis gajah (Garcinia griffithii) dan aktifitas aktioksidannya. Disertasi Universitas Padjajaran, 2008.

Zhang, N. P. Seeram, R. Lee, Isolation and identification of strawberry phenolics with antioxidant and cancer cell antipoliferative, Agric. Food chem., 56(3): 670-675.

Muharni, Phenolic compound from the stem bark of manggis hutan (Garcinia bancana) and their antioxidant activity, Indo. J. Chem. 9 (20): 321-327, (2009).

H. Minami, K. Hamaguchi, and M. Kubo, a benzophenone and a xanthone from garcinia subelliptica, Phytochemistry., 49(6): 1783-1785, (1998).

P. Molyneux P. The use of the stable free radicals diphenylpicrylhydrazyl (DPPH)

for estimating antioxidant activity, Song-klanakarin J. Sci. Technol., 26(2): 211-219, (2004).

Article Metrics

Metrics Loading ...

Metrics powered by PLOS ALM